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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUX1
All Species:
21.52
Human Site:
Y149
Identified Species:
39.44
UniProt:
P39880
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P39880
NP_853530.2
1505
164273
Y149
L
K
E
K
I
R
E
Y
E
Q
T
L
K
N
Q
Chimpanzee
Pan troglodytes
XP_527845
1515
165612
Y160
L
K
E
K
I
R
E
Y
E
Q
T
L
K
N
Q
Rhesus Macaque
Macaca mulatta
XP_001114534
1791
194745
Y426
L
K
E
K
I
R
E
Y
E
Q
T
L
K
N
Q
Dog
Lupus familis
XP_546939
1411
154543
E139
V
R
R
R
L
E
G
E
R
K
R
R
G
S
G
Cat
Felis silvestris
Mouse
Mus musculus
P53564
1515
165577
Y149
L
K
E
K
I
R
E
Y
E
Q
T
L
K
S
Q
Rat
Rattus norvegicus
P53565
862
92341
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506212
1543
168501
L195
S
P
T
G
I
T
V
L
E
G
R
R
F
T
G
Chicken
Gallus gallus
XP_425393
1673
183755
Y294
L
K
E
K
I
R
E
Y
E
Q
T
L
K
N
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693902
1398
154481
G125
A
A
S
S
F
L
S
G
V
S
V
T
C
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10180
2175
233610
P316
Q
Q
E
T
R
T
E
P
S
A
T
T
Q
Q
Q
Honey Bee
Apis mellifera
XP_623857
1936
209316
L187
A
E
K
E
V
S
A
L
K
E
Q
L
A
A
A
Nematode Worm
Caenorhab. elegans
Q9BL02
1273
143507
A60
N
K
D
S
R
K
V
A
I
P
L
I
K
A
F
Sea Urchin
Strong. purpuratus
XP_780858
1460
163719
Y161
L
Q
T
K
L
K
E
Y
E
E
R
S
E
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
83.1
56.2
N.A.
88.8
47.1
N.A.
44.3
77.4
N.A.
40.9
N.A.
23.3
23.7
22.3
29.1
Protein Similarity:
100
98.6
83.4
64.5
N.A.
91.8
50
N.A.
60
81.7
N.A.
55.4
N.A.
37.4
41
41
46.6
P-Site Identity:
100
100
100
0
N.A.
93.3
0
N.A.
13.3
100
N.A.
0
N.A.
26.6
6.6
13.3
33.3
P-Site Similarity:
100
100
100
40
N.A.
100
0
N.A.
13.3
100
N.A.
0
N.A.
40
46.6
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
0
0
8
8
0
8
0
0
8
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
47
8
0
8
54
8
54
16
0
0
8
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
16
% F
% Gly:
0
0
0
8
0
0
8
8
0
8
0
0
8
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
47
0
0
0
8
0
0
8
0
0
0
% I
% Lys:
0
47
8
47
0
16
0
0
8
8
0
0
47
0
0
% K
% Leu:
47
0
0
0
16
8
0
16
0
0
8
47
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
31
0
% N
% Pro:
0
8
0
0
0
0
0
8
0
8
0
0
0
0
0
% P
% Gln:
8
16
0
0
0
0
0
0
0
39
8
0
8
8
47
% Q
% Arg:
0
8
8
8
16
39
0
0
8
0
24
16
0
0
0
% R
% Ser:
8
0
8
16
0
8
8
0
8
8
0
8
0
24
0
% S
% Thr:
0
0
16
8
0
16
0
0
0
0
47
16
0
8
0
% T
% Val:
8
0
0
0
8
0
16
0
8
0
8
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _